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Biochemistry topics for USMLE Step 1

Biochemistry topics for USMLE Step 1

Biochemistry and molecular biology

  • energy metabolism, including metabolic sequences and regulation
    • generation of energy from carbohydrates, fatty acids, and essential amino acids; glycolysis, pentose phosphate pathway, tricarboxylic acid cycle, ketogenesis, electron transport and oxidative phosphorylation, glycogenolysis
    • storage of energy: gluconeogenesis, glycogenesis, fatty acid and triglyceride synthesis
    • thermodynamics: free energy, chemical equilibria and group transfer potential, energetics of ATP and other high-energy compounds
  • metabolic pathways of small molecules and associated diseases
    • biosynthesis and degradation of amino acids (eg, homocystinuria, maple syrup urine disease)
    • biosynthesis and degradation of purine and pyrimidine nucleotides
    • biosynthesis and degradation of lipids (eg, dyslipidemias, carnitine deficiency)
    • biosynthesis and degradation of porphyrins
    • galactosemia and other small sugar disorders
    • biosynthesis and degredation of alcohols and other small molecules
  • biosynthesis and degradation of other macromolecules and associated abnormalities, complex carbohydrates (eg, lysosomal storage disease), glycoproteins, and proteoglycans (eg, type II glycogen storage disease)

Biochemistry and molecular biology for USMLE Step 1

source: http://usmle.org/Examinations/step1/content/principles.html

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Categorised as: Biochemistry 1


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