Dermatology topics for USMLE Step 1
Dermatology topics for USMLE Step 1
Skin and Related Connective Tissue
Normal processes
- embryonic development, fetal maturation, and perinatal changes
- organ structure and function
- cell/tissue structure and function, including barrier functions, thermal regulation, eccrine function
- repair, regeneration, and changes associated with stage of life or ethnicity (eg, senile purpura, male pattern baldness, postmenopausal hair changes)
- skin defense mechanisms and normal flora
Abnormal processes
- infectious, inflammatory, and immunologic disorders
- bacterial infections (eg, acne, cellulitis, carbuncle, abscess, necrotizing fasciitis, gangrene)
- viral infections (eg, herpes infections, chickenpox, rubella, measles, roseola, verrucae)
- fungal infections, including mycoses, dermatophytosis (eg, tinea)
- parasitic infections (eg, scabies, lice)
- immune and autoimmune disorders (eg, discoid lupus erythematosus, scleroderma, dermatomyositis, alopecia, psoriasis, urticaria, allergic dermatosis)
- traumatic and mechanical disorders (eg, thermal injury, decubitus ulcers, effects of ultraviolet light and radiation)
- neoplastic disorders
- keratinocytes (eg, seborrheic keratosis, actinic keratosis, basal cell carcinoma, squamous cell carcinoma, and ichthyosis)
- melanocytes (eg, nevi, melanoma)
- vascular neoplasms (eg, hemangiomas, Kaposi sarcoma)
- other (eg, T-cell lymphoma, skin appendage tumors)
- metabolic, regulatory, and structural disorders (eg, vitamin deficiencies, hypervitaminosis, hyperhidrosis)
- vascular disorders (eg, vasculitis, Raynaud disease)
- systemic disorders affecting the skin (eg, Ehlers-Danlos syndrome, Marfan syndrome)
Principles of therapeutics
- mechanisms of action, use, and adverse effects of drugs for treatment of disorders of the skin and connective tissue, including anti-inflammatory agents (eg, corticosteroids, antihistamines), emollients, sunscreen, retinoids, antimicrobial agents, cytotoxic and immunologic therapy (eg, methotrexate, PUVA, keratinolytics)
- other therapeutic modalities (eg, laser, tattoo removal, cryotherapy)
Gender, ethnic, and behavioral considerations affecting disease treatment and prevention, including psychosocial, cultural, occupational, and environmental
- emotional and behavioral factors (eg, sun exposure, acne)
- influence on person, family, and society (eg, psoriasis)
- occupational and other environmental risk factors
- gender and ethnic factors (eg, keloid)
usmle.org
Categorised as: Dermatology 1